Zeobel: Xeomin and Belotero Premium Skin Booster, Step by Step
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Zeobel: Xeomin and Belotero Premium Skin Booster, Step by Step

A step-by-step look at Zeobel, the premium skin booster injection that blends the German toxin Xeomin with the hyaluronic acid Belotero.

Table of Contents

Two treatments can share the name skin booster injection and still turn out differently, depending on which products go in and how they are delivered. This article follows the steps of Skinique Clinic's premium skin booster, known in the clinic as Zeobel, which blends the German botulinum toxin Xeomin with the hyaluronic acid filler Belotero, and looks at how it differs from a standard skin booster injection.

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The two products used in Zeobel

Zeobel places a measured blend of Belotero Soft and Xeomin into the dermis. It is not unusual for someone to receive a skin booster injection without ever learning which products were used, and knowing what went into your skin is quite different from not knowing.

Belotero Soft is a hyaluronic acid product made with the CPM process patented in Switzerland, and it has US FDA approval. Its particles are fine and stabilized, so it sits closely within the skin, and because each small HA particle can hold many times its own weight in water molecules, it lends itself to restoring hydration and a natural sense of firmness.

Xeomin, added to that blend, is a botulinum toxin refined through Merz's own biotechnology purification process, which lowers the likelihood of resistance developing, and it allows fine lines and pore concerns to be addressed at the same time. In short, the combination aims at the hydration and firmness of hyaluronic acid alongside the texture refinement of skin Botox in a single session.

Preparing before the treatment

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As the seasons turn, noticeably more people come in with concerns about dryness and pores. The patient in the photo also decided to go ahead with Zeobel after a full consultation.

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Once the treatment is decided, it starts with applying numbing cream and waiting for it to take effect. At Skinique Clinic, patients are not left to handle this alone; an aesthetician assists directly, from cleansing through to applying the cream.

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Just before injection, the products to be used are checked and opened in front of the patient. The Xeomin and 1cc of Belotero opened this way are then mixed evenly in a single syringe and made ready.

Why the injection is done with Dermashine Pro

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The injection itself is carried out with a Dermashine Pro device. Many people assume manual injection is always better, but this device lifts the skin slightly with negative pressure as it delivers the product, so less of it is lost, and the depth and spacing within the dermis stay more consistent than with manual injection. Because it uses fine micro-needles, much of the discomfort and the raised bumps that make injection treatments daunting can also be reduced.

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The numbing cream is wiped off and the whole face is disinfected before the treatment proper begins. Taking care of the awkward corners that are harder to treat is something patients at Skinique Clinic often mention.

Aftercare and recovery

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Once the injection is finished, fine needle marks remain on the surface of the skin.

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A modeling pack is applied straight away to calm the skin, basic skincare is put back in order, and you can head home once the redness has settled. Needle marks usually fade naturally within two to three days, though recovery speed varies from person to person.

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Details on cost are available on the pricing guide.

Wrapping Up

Zeobel is a premium skin booster injection that adds the toxin Xeomin to the well-established hyaluronic acid Belotero, addressing hydration and firmness alongside fine lines and pore concerns in one session, with device-assisted delivery to reduce discomfort and product loss. If you would like to know whether it suits your skin, feel free to ask through a chat consultation about the right direction for your skin.


This article was written by Dr. Park Tae-hyung, Chief Director. He is the chief director of Skinique Clinic and serves as an academic director of the Korean Society for Laser Dermatology and Trichology. First published October 11, 2022 · Last reviewed August 24, 2026


This article is general medical information. Skin condition and response to treatment can vary from person to person. Please decide whether and how to be treated through an in-person consultation.