ECM Skin Booster and Liquid PCL Explained: A Conference Log
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ECM Skin Booster and Liquid PCL Explained: A Conference Log

How the ECM skin booster (Re2O) and liquid PCL (Gouri) work, and notes from a practitioner who lectures on them at academic congresses.

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Once you start looking into skin boosters, unfamiliar names such as Re2O and Gouri come pouring in, and it is easy to feel lost about what criteria to choose by. This piece sets out how these newer formulations actually work, and how medical practitioners verify and learn about them, alongside notes from a conference floor.

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On the floor at the Korean Society for Laser Dermatology and Trichology

On May 3, 2026, the annual congress of the Korean Society for Laser Dermatology and Trichology was held at COEX. It is a gathering where practitioners in skin care from across the country share the evidence behind the latest treatments and their clinical experience, and over that single day Chief Director Park Tae-hyung took the stage for seven lectures and chaired two sessions.

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A conference lecture given to an audience of fellow practitioners is different in character from an explanation given to patients. You need the theoretical grounding for a treatment's mechanism of action, the clinical data that has accumulated, and the know-how gained in actual practice, before you can stand in front of colleagues. Of the topics covered at this congress, here are two that patients may find of interest.

The ECM skin booster, an approach that refills the skin's framework

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The ECM skin booster, known by the name Re2O, uses extracellular matrix (ECM) components obtained from acellular allogeneic dermis. The ECM corresponds to the structure within the skin that supports collagen and elastin so that they can settle into place, and the core concept of this treatment is to replenish that framework component and create an environment in which the skin can recover on its own. In that it seeks to address the skin's foundation itself rather than stopping at simply delivering an ingredient, it is different in character from existing skin boosters. Chief Director Park Tae-hyung gave a lecture on what this ECM skin booster means in clinical practice and on strategies for its use.

Liquid PCL, and what changes when the formulation changes

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Another topic was the liquid PCL category, represented by Gouri. Like the PDLLA familiar from Juvelook, it is an ingredient that prompts the body to produce its own collagen, but its distinguishing feature is that it is made as a liquid formulation from the outset rather than as a powder to be reconstituted. A liquid formulation spreads evenly within tissue, and is designed in the direction of lowering the likelihood of clumping (nodules), which gives it certain advantages when working naturally across a broad area. That said, precisely because it spreads well, where and in which direction it is injected governs the result, and so Chief Director Park Tae-hyung centred his lecture on vector design and injection technique grounded in facial anatomy.

What a lecturing practitioner does differently in the consulting room

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Rather than following each new treatment by name alone as it appears, going through the process of studying its ingredients and mechanism directly and having that scrutinised in front of fellow practitioners changes the criteria for judgement in the consulting room as well. It becomes possible to decide, with grounds, which formulation suits which skin, and at what depth and in what manner it should be placed. This is why SKINIQUE Clinic regards its academic activity as an extension of clinical practice.

Wrapping Up

At this congress, Chief Director Park Tae-hyung lectured and chaired on the clinical use of the ECM skin booster and on anatomy-based injection design for liquid PCL. Skin boosters differ in ingredient and mechanism from one to the next, so what matters is a choice suited to the state of your own skin rather than what is in fashion. If you are wondering which approach fits you, feel free to ask through a chat consultation on the skin booster suited to your skin.


This article was written by Dr. Park Tae-hyung. He is the Chief Director of SKINIQUE Clinic and serves as Senior Director of the Korean Society for Laser Dermatology and Trichology. First published May 13, 2026 · Last reviewed August 23, 2026


This text is general medical information. Skin condition and response to treatment vary from person to person. Please decide whether and how to undergo treatment through an in-person consultation.