If your skin still feels tight no matter how much moisturizer you apply, the issue may not be the surface but a lack of water in the dermis. Skincare products have a hard time getting past the skin barrier. This article looks at skin booster injections that deliver hydration directly into the dermis, and specifically at the Byryzn and skin Botox combination used at SKINIQUE Clinic.
What a skin booster injection addresses
A skin booster injection, often called a glow injection, delivers a hyaluronic acid based product into the dermal layer. Hyaluronic acid can hold up to 1,000 times its own weight in water, so placing it inside the skin allows moisture to stay longer and helps the oil and water balance settle. What matters is that the same name can mean very different products from clinic to clinic. Since the type of hyaluronic acid influences both the result and how long it lasts, checking the product itself comes first.
Why Byryzn
Byryzn is a skin booster made by Hugel and approved as a medical device by Korea's Ministry of Food and Drug Safety (MFDS). It contains 20 mg of hyaluronic acid that has been cross-linked for greater cohesiveness, which is a generous amount, and clinical research published in SCI-indexed international journals has reported improvement across several skin measures including wrinkles, roughness, elasticity, pores, hydration and radiance. Study findings do not apply identically to everyone, and individual responses vary.
At SKINIQUE Clinic we also offer the option of mixing in skin Botox. The combination aims at fine lines, pores and subtle firmness alongside hydration and radiance.
The procedure, step by step
Once the treatment is decided in consultation with the doctor, numbing cream is applied over the whole face and we wait until the surface is sufficiently desensitized.
Before the treatment begins, we show you the product that will be used and open it in front of you.
If you are adding skin Botox, we also show you the toxin product you selected and mix it with Byryzn on the spot. This step is skipped when Byryzn is used on its own.
Here is the mixed solution, ready to use.
Injection is done with the Dermashine Pro device. Negative pressure lifts the skin slightly while fine tips deliver the solution, which allows more even and closely spaced placement in the dermis than manual injection.
Because the solution goes directly into the skin, some discomfort is possible. We work carefully to limit pain and embossing (small raised bumps), but injection marks can remain for a few days, so it helps to leave some room in your schedule.
Forehead, cheeks, chin, eye area, around the mouth and the nose: the injection covers the whole face evenly, without skipping the spots where dryness tends to show.
When the injection is finished, a modeling pack calms the flushed skin, followed by a light basic skincare routine before you head home.
Full pricing is available on the price guide.
Wrapping Up
Dehydration deep in the skin is difficult to solve with skincare alone, and a skin booster injection that places moisture directly into the dermis can be one alternative. Since the choice of product shapes the outcome, it is worth confirming which solution is used and how it is injected before you decide. If you are wondering whether Byryzn alone or the skin Botox combination suits your skin, ask us by chat about the right option for your skin.
This article was written by Dr. Park Tae-hyung, Chief Director. He is the chief director of SKINIQUE Clinic and serves as academic director of the Korean Society for Laser Dermatology and Trichology. First published September 13, 2023 · Last reviewed August 24, 2026
This article is general medical information. Skin condition and response to treatment vary from person to person. Whether and how to treat should be decided through an in-person consultation.