Acne is the kind of concern that tends to return to the same spot: even when the visible inflammation settles down, breakouts come back if sebum production and the inflammatory environment are left unchanged. In this article we explain how Potenza, exosomes, NeoBeam and PlaDuo - the treatments SKINIQUE Clinic uses for acne - each work, and why they are combined into one program.

Acne care starts with managing the cause
Acne develops when sebum, increased by a number of factors, blocks the follicle and inflammation progresses inside it. That is why both axes - reducing sebum production and controlling inflammation - need to be managed for the skin to reach a state where acne is less likely to keep recurring.
SKINIQUE Clinic's acne program is designed from this perspective. A session combining the Potenza N16 tip, exosomes (Exomit) and NeoBeam alternates every one to two weeks with a session combining NeoBeam and PlaDuo, so that treatments working through different mechanisms each take on their own role across multiple visits.

Potenza: RF microneedling that addresses sebaceous glands and inflammation together
Potenza is an RF microneedling device that delivers radiofrequency energy into the dermis through fine needles. The radiofrequency delivered to the dermis stimulates collagen production, which improves the skin environment itself, while also working to reduce the size of the sebaceous glands behind acne and to calm inflammation that is already under way. In other words, it targets both the acne you can see now and the acne that may form later.

Exosomes: anti-inflammatory ingredients delivered through the channels the needles create
Among skin boosters, exosomes are characterised by their anti-inflammatory and antibacterial action. Immediately after a Potenza session the micro-channels created by the needles are still open, so applying or injecting exosomes at that moment gives the ingredients favourable conditions to reach the dermis. They help manage the bacteria and inflammation involved in acne while also supporting regeneration and nourishment as damaged skin recovers.

NeoBeam: a laser that selectively targets the sebaceous glands
NeoBeam (1450nm sebum-control laser) is a laser that selectively damages the sebaceous glands to reduce sebum production. Depending on the wavelength band, it responds to the "water" within inflammation and to the "oil" within the sebaceous glands, so it can address both causes of acne directly. When sebum output falls, it helps not only with current breakouts but also with reducing recurrence, and because it stimulates collagen production it is also used in the care of acne scarring. Delivered immediately after Potenza, the energy travels more easily along the channels the needles have created and reaches the deeper dermis, so a synergy can be expected that differs from the laser used on its own.

PlaDuo: managing bacteria and inflammation with plasma
RF microneedling is a treatment received at intervals of roughly four weeks, and acne keeps appearing in between. That is why NeoBeam + PlaDuo sessions are placed in the middle of the program, so that sebum and inflammation are managed at closer intervals.

PlaDuo (dual plasma) is a dual plasma device using argon and nitrogen, and its role is to reduce acne-causing bacteria, ease inflammation, help regulate the sebaceous glands and support skin recovery. Paired with NeoBeam, it allows sebum, inflammation and bacteria - the core loop of acne - to be addressed together within a single session.

Why a combination program
To sum up, this program assigns skin-environment improvement (Potenza), anti-inflammatory and antibacterial action (exosomes, PlaDuo) and sebaceous gland regulation (NeoBeam, PlaDuo) to separate roles, taking the interaction between the treatments into account as well. That said, the combination and number of sessions that suit you will vary with your skin type, and results differ from person to person.

Wrapping Up
With recurring acne, the key is to address both underlying factors - sebum production and inflammation - and this combination program tackles those causes by dividing the roles between treatments. Whether to proceed and how the program is put together are best decided through a consultation, and detailed costs can be found on the price guide. If you would like to know what lies behind your recurring breakouts, please get in touch via chat with us about the right direction for your skin.
This article was written by Dr. Park Tae-hyung, Chief Director. He is the Chief Director of SKINIQUE Clinic and serves as Senior Director of the Korean Society for Laser Dermatology and Trichology.
First published May 17, 2024 · Last reviewed August 23, 2026
This article is general medical information. Skin condition and response to treatment may vary from person to person. Please decide whether and how to be treated through a medical consultation.
