When people first look into skin boosters, Rejuran is usually the first name they come across. It is widely available, yet there is surprisingly little organized information on how to choose a clinic. This article covers what makes Rejuran distinctive, why we use Rejumate, the dedicated injection device, and what to check when choosing a clinic.
The Rejuran Line: What Sets Each Product Apart
Rejuran, released as a medical device by PharmaResearch, comes in four versions depending on the intended use: the standard formula for the full face, Rejuran I for thin areas such as the eye area and under-eyes, Rejuran S for depressed scars, and HB Plus with added hydration.
The common active ingredient is polynucleotide (PN) derived from salmon, a substance that supports skin cell regeneration. Compared with the PDRN family, often called the "salmon DNA injection," PN is a higher-grade ingredient in concentration and molecular weight, and it focuses on improving the dermal environment itself.
True to the name "Healer," this treatment aims to increase dermal density, refine skin texture and the oil-moisture balance, and support the recovery of thin, sensitized skin or a weakened skin barrier. Of course, responses vary from person to person.
An authentic box contains a sealed 2cc syringe, and the standard is to use this full amount in a single session.
Verifying Authentic Product and Full Dosage Comes First
At Skinique Clinic, a Rejuran session proceeds in this order: consultation with the doctor, cleansing and numbing cream application, verification of the product to be used, the treatment itself, and soothing care. The third step, product verification, deserves your attention.
Whether the clinic opens the sealed product in front of you to show its authenticity and manufacturing date, and whether the full 2cc is actually used, are among the few quality indicators a patient can check directly. Skinique Clinic makes it a rule to show this process right before the treatment, because we believe that honestly using the proper product in the proper amount is where results begin.
Rejumate: A Device Built to Manage Pain
Browse Rejuran reviews and you will always find the debate over manual injection versus device-assisted injection. Skinique Clinic uses Rejumate, the injection device the manufacturer developed specifically for Rejuran. Its multiple fine needles deliver the PN evenly and densely into the dermis, and compared with manual injection it reduces pain during the procedure as well as the raised bumps that appear right after injection. There is a common belief that device injection wastes more product, but this depends on how the treatment is performed rather than on the device itself.
Rejumate allows the injection depth and the volume per pass to be adjusted. Since the pain of Rejuran comes mainly from the viscous formula entering the dermis rather than from the needle prick, adjusting the injection volume to your pain sensitivity makes the treatment considerably more comfortable. This kind of individual adjustment takes more time, but Skinique Clinic prioritizes tailoring both the process and the outcome to each patient, based on what the doctor learns in the consultation.
Easing pain as we work, while accounting for the areas that need focus and the thickness of your skin: this is the principle we hold to.
Three Criteria for Choosing a Clinic
In short, when choosing a clinic for Rejuran, we recommend checking these three things rather than debating price or injection method. First, can you communicate sufficiently with the medical staff from consultation through treatment? Second, does the clinic transparently disclose product authenticity, dosage, and manufacturing date? Third, does it tailor the treatment to your skin concerns instead of following a fixed routine?
Wrapping Up
Because Rejuran is a skin booster that works on the dermal environment at its root, satisfaction varies with how the product is managed and how the treatment is performed. The key is choosing a clinic that verifies authentic products and offers customized injection. For detailed costs, see Treatment Prices. If you are wondering whether Rejuran suits your skin, feel free to chat with us about the right direction for your skin.
This article was written by Dr. Park Tae-hyung, Chief Director of Skinique Clinic and an academic director of the Korean Society for Laser, Dermatology and Trichology. First published March 7, 2023 · Last reviewed August 24, 2026
This article is general medical information. Skin conditions and responses to treatment vary from person to person. Please decide whether and how to proceed with treatment through an in-person consultation.