Look into skin boosters and one name keeps coming up: exosomes. There are many versions, and each product highlights something different, which makes it hard to know what to judge them by. This article sets out what exosomes actually are, how the two products used at Skinique Clinic differ, and what you gain by combining them with Potenza.
Exosomes, the Messengers Between Cells
Exosomes are very small sac-like vesicles that carry signals between cells. Regarded as the key component of stem cell culture media, they hold biologically derived substances and relay anti-inflammatory and regenerative signals to the skin. Exosome products used as skin boosters are formulated to deliver those active components deep into the skin efficiently, and because their calming action on inflammation is pronounced, they are often chosen for skin prone to breakouts. How much the skin responds does vary from person to person.
The Two Exosome Products Skinique Uses
Many exosome products are on the market, but after internal review Skinique Clinic uses only two of them: ASCE+ and NeoStem. ASCE+ is produced with a patented purification technology called ExoSCRT, which isolates exosomes from stem cell culture media at high purity. It comes as a freeze-dried first vial and an activating second vial, mixed together just before the treatment.
NeoStem is a liquid formulation made through a proprietary three-dimensional culture method, a high-purity, high-concentration exosome product with no antibiotics or preservatives added. What distinguishes it is that it is designed to keep the properties of its active components intact in liquid form.
The formulations and manufacturing methods differ, but both are skin boosters pointing in the same direction: calming inflammation, supporting regeneration, and improving the skin barrier. Which one to use, or whether another skin booster such as Rejuran or Juvelook would suit your skin better, is decided together with the medical team in a one-on-one consultation before treatment, based on the condition of your skin.
What Changes When a Potenza Tip Delivers It
Exosomes can be given on their own, but they can also be introduced using Potenza's pumping tip. A tip with fine needles arranged closely together pushes the solution evenly down into the dermal layer while radiofrequency energy is added, so delivery of the solution and collagen stimulation happen together in a single session.
How the Treatment Proceeds
Walking through an exosome and Potenza session: after thorough cleansing, numbing cream is applied evenly across the entire face to reduce discomfort. The wide area of application also reflects that the treatment covers the face as a whole. Once the numbing has taken effect the cream is wiped off and the treatment itself is prepared. At this stage we show you the unsealing of a new product, the amount used, and the empty vial left afterwards, right in front of you. It is how we demonstrate our rule of using genuine products in full measure.
The cp-25 tip used with Potenza is likewise unsealed in front of you before the treatment begins, so there is no need to worry about a tip being reused.
During the session we talk you through which area we are working on and how, and even under the same treatment name we shift the emphasis depending on your facial structure and skin condition. We do so because we believe that when the same device and the same product produce different results from one clinic to another, the difference ultimately lies in the hands of the person performing it.
Detailed costs are available on the price guide.
Wrapping Up
Exosomes are skin boosters centered on calming inflammation and supporting regeneration, and pairing them with Potenza's pumping tip lets you aim for delivery of the solution and radiofrequency stimulation at once. Which product and combination suits your skin is most accurately settled in consultation. If anything is unclear, feel free to ask through chat about the skin booster that fits your skin.
This article was written by Dr. Park Tae-hyung, Chief Director. He is the chief director of Skinique Clinic and serves as academic director of the Korean Society for Laser Dermatology and Trichology. First published October 4, 2023 · Last reviewed August 24, 2026
This article is general medical information. Skin condition and response to treatment can vary from person to person. Whether and how to treat should be decided through an in-person consultation.